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Charles Erlichman Selected Research

temsirolimus

5/2015Multicenter Phase II Trial of Temsirolimus and Bevacizumab in Pancreatic Neuroendocrine Tumors.
3/2015Safety and activity of temsirolimus and bevacizumab in patients with advanced renal cell carcinoma previously treated with tyrosine kinase inhibitors: a phase 2 consortium study.
2/2015A phase II trial of bevacizumab plus temsirolimus in patients with advanced hepatocellular carcinoma.
5/2013A phase I trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer.
10/2012Phase I study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors.
8/2011A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas: a study of the Mayo phase 2 consortium (P2C).
4/2011Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study.
6/2010Phase I, pharmacokinetic study of temsirolimus administered orally to patients with advanced cancer.
10/2006A phase I and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer.

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Charles Erlichman Research Topics

Disease

75Neoplasms (Cancer)
01/2022 - 03/2002
11Breast Neoplasms (Breast Cancer)
11/2017 - 09/2006
10Fatigue
03/2016 - 06/2005
9Diarrhea
02/2015 - 01/2005
8Disease Progression
01/2019 - 06/2005
8Nausea
03/2016 - 04/2004
7Pancreatic Neoplasms (Pancreatic Cancer)
09/2020 - 08/2008
7Neutropenia
06/2017 - 03/2002
7Colorectal Neoplasms (Colorectal Cancer)
05/2017 - 08/2005
7Vomiting
03/2016 - 02/2005
7Carcinoma (Carcinomatosis)
05/2014 - 04/2005
5Adenocarcinoma
01/2020 - 11/2004
5Ovarian Neoplasms (Ovarian Cancer)
11/2013 - 12/2003
4Neuroendocrine Tumors (Neuroendocrine Tumor)
11/2021 - 04/2005
4Thyroid Neoplasms (Thyroid Cancer)
01/2020 - 10/2010
4B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
08/2017 - 08/2009
4Exanthema (Rash)
03/2016 - 06/2005
4Mucositis
02/2015 - 09/2005
4Thrombocytopenia (Thrombopenia)
01/2012 - 09/2005
4Neoplasm Metastasis (Metastasis)
12/2006 - 01/2005
3Colonic Neoplasms (Colon Cancer)
11/2021 - 02/2002
3Primitive Neuroectodermal Tumors (PNET)
11/2021 - 02/2008
3B-Cell Lymphoma (Lymphoma, B Cell)
01/2019 - 01/2002
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
07/2015 - 07/2005
3Hypertension (High Blood Pressure)
05/2015 - 09/2012
3Hepatocellular Carcinoma (Hepatoma)
02/2015 - 02/2012
3Multiple Myeloma
01/2015 - 03/2006
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2013 - 05/2003
3Sarcoma (Soft Tissue Sarcoma)
08/2011 - 05/2005
3Melanoma (Melanoma, Malignant)
07/2010 - 06/2005
3Non-Hodgkin Lymphoma (Lymphosarcoma)
10/2009 - 01/2002
2Hypokalemia
01/2019 - 01/2005
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
07/2015 - 01/2012
2Lymphopenia (Lymphocytopenia)
05/2015 - 04/2011
2Abdominal Pain (Pain, Abdominal)
10/2013 - 10/2009
2Anaplastic Thyroid Carcinoma
09/2012 - 10/2010
2Liver Neoplasms (Liver Cancer)
05/2012 - 09/2005
2Headache (Headaches)
01/2012 - 10/2009
2Anemia
01/2012 - 02/2005

Drug/Important Bio-Agent (IBA)

13tanespimycin (17AAG)IBA
08/2015 - 02/2005
12Proteins (Proteins, Gene)FDA Link
01/2019 - 07/2003
11GemcitabineFDA Link
01/2020 - 01/2003
9ErbB Receptors (EGF Receptor)IBA
01/2020 - 09/2005
9temsirolimusFDA Link
05/2015 - 10/2006
8Pharmaceutical PreparationsIBA
11/2017 - 10/2006
8Bortezomib (Velcade)FDA Link
10/2013 - 05/2005
7Bevacizumab (Avastin)FDA Link
11/2021 - 04/2007
7Cisplatin (Platino)FDA LinkGeneric
08/2014 - 07/2003
7Carboplatin (JM8)FDA LinkGeneric
07/2010 - 08/2002
6pazopanibFDA Link
01/2020 - 07/2010
6Phosphotransferases (Kinase)IBA
05/2014 - 04/2005
6TOR Serine-Threonine KinasesIBA
05/2013 - 10/2005
6Irinotecan (Camptosar)FDA LinkGeneric
01/2012 - 05/2003
6Fluorouracil (Carac)FDA LinkGeneric
07/2011 - 03/2002
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 12/2010
5Biomarkers (Surrogate Marker)IBA
01/2020 - 09/2012
5Rituximab (Mabthera)FDA Link
08/2017 - 01/2002
5Hormones (Hormone)IBA
03/2016 - 04/2005
4Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2021 - 10/2003
4Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2020 - 09/2005
4DNA (Deoxyribonucleic Acid)IBA
10/2018 - 08/2005
4Estrogen ReceptorsIBA
11/2017 - 05/2013
4MK 2206IBA
11/2017 - 05/2014
4Paclitaxel (Taxol)FDA LinkGeneric
06/2017 - 03/2005
4Tyrosine Kinase InhibitorsIBA
03/2015 - 07/2010
4Heat-Shock Proteins (Heat-Shock Protein)IBA
11/2011 - 07/2005
4Insulin ReceptorIBA
01/2011 - 01/2006
4Transaminases (Aminotransferases)IBA
06/2010 - 04/2004
4Leucovorin (Folinic Acid)FDA Link
05/2007 - 05/2002
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2022 - 09/2012
3Biological ProductsIBA
01/2018 - 04/2007
3Topotecan (Hycamtin)FDA LinkGeneric
01/2018 - 09/2005
3EKB 569IBA
10/2012 - 05/2006
3alvocidib (flavopiridol)IBA
10/2012 - 08/2005
3BMS 536924IBA
01/2011 - 09/2008
3Proteasome InhibitorsIBA
02/2007 - 05/2005
3TransferasesIBA
03/2005 - 05/2003
2cediranib (AZD2171)IBA
01/2022 - 07/2015
2Sodium Glutamate (Accent)IBA
11/2021 - 01/2021
2HhAntag691IBA
09/2020 - 01/2020
2GossypolIBA
01/2019 - 10/2011
2gossypol acetic acidIBA
01/2019 - 10/2011
2Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2018 - 07/2011
2veliparibIBA
01/2018 - 07/2011
2Estrogens (Estrogen)FDA Link
11/2017 - 01/2016
2Anastrozole (Arimidex)FDA LinkGeneric
11/2017 - 01/2016
2TamoxifenFDA LinkGeneric
10/2017 - 03/2016
2Sorafenib (BAY 43-9006)FDA Link
02/2016 - 10/2013
2Monoclonal AntibodiesIBA
05/2015 - 10/2009
2CamptothecinIBA
05/2014 - 05/2003
2Etoposide (VP 16)FDA LinkGeneric
05/2014 - 10/2005
2Insulin-Like Growth Factor I (IGF-1)IBA
05/2013 - 09/2008
2polyphenon EIBA
01/2013 - 08/2009
2belinostatIBA
09/2012 - 01/2012
2Histone Deacetylase InhibitorsIBA
09/2012 - 01/2012
2Cytarabine (Cytosar-U)FDA LinkGeneric
11/2011 - 07/2005

Therapy/Procedure

32Therapeutics
11/2021 - 02/2002
11Drug Therapy (Chemotherapy)
03/2016 - 02/2002
5Drug Tapering
09/2012 - 07/2006
3Radiotherapy
03/2016 - 05/2003